Back  |
-
Subscribe to newsletter
 News
-
Get listed our directory
Pharmaceutical Research Centers
Jordan's Associations
Dental Laboratories
Nursing Centers
Medical Centers
Fitness Centers
Beauty Centers
Optic Centers
Drugstores
Hospitals
Doctors
Dentists
Dietitian
Companies
Pharmacies
Dental Centers
Herbal Centers
Scientific Offices
Infertility Centers
Dead Sea Factories
Medical Laboratories
Pharmaceutical Factories
Rheumatoid Arthritis Treatment: The FDA has approved anakinra as adjunctive therapy for..

The FDA has approved anakinra (Kineret Amgen Inc, Thousand Oaks, Calif) as adjunctive therapy for reduction in signs and symptoms of moderately to severely active rheumatoid arthritis (RA) in patients 18 years of age or older in whom one or more disease-modifying antirheumatic drugs (DMARDs) have failed. Anakinra is indicated for use alone or in combination with DMARDs other than anti–tumor necrosis factor (TNF) therapies.

Safety and effectiveness of were evaluated in three randomized, placebo-controlled trials of 1392 patients at least 18 years of age with active RA. A fourth study assessed the drug's safety in 1414 similar patients who were DMARD free or received concurrent medications, including some DMARDs.

Anakinra was studied in combination with DMARDs (other than anti-TNF therapies) or as monotherapy. Results were assessed using American College of Rheumatology (ACR) response criteria. In all three studies, patients taking anakinra were more likely to achieve scores of ACR 20, ACR 50, or ACR 70 than patients treated with placebo. In the largest study, patients with RA receiving a stable dose of methotrexate were also treated with anakinra, 100 mg/d (the recommended dosage), or placebo. After 3 months, 34% of patients receiving anakinra and 24% patients receivingon placebo had ACR 20.

Adverse reactions associated with the drug included increased incidence of serious infections (2% in those taking the drug vs <1% in those taking placebo) and neutropenia. Preliminary data suggest a much higher rate of serious infections and neutropenia when anakinra is used with an anti-TNF therapy.


 

Published on 11 January 2002
 
 
  Are You interested to promote your self @ Yemen, Bahrain, Sudan, Libya & Arbeel?
  Severe stress in pregnancy may affect fetal growth
  Weight loss may cut risk of colorectal growths
  Flu shot does not cut risk of death in elderly
  Low Levels of Brain Chemical May Control Appetite
  Most Patients With Irregular Heartbeat Take Inadequate Blood Thinner Dose
  Wearing an underwire bra increases your risk of getting breast cancer
  Businesswomen from Uganda and Ghana were second and third as Jordanian entrepreneur takes first prize at UNCTAD’s debut women in business awards
  Jordanian Woman Wins First Prize: Sana Burgan
  "Concept, Indication and Handling of the Friadent Implant System Xive" courses will be held in Jordan Soon

  Dr. Joudeh Operated on a big Tumor.....

  HealLand Newspaper
  HealLand Jordan Directory
  Happy Eid
  Are You Targeting Jordan, Yemen, Bahrain and All the Arabic World
  Afurnished Clinic 4 Rent..

  Med Grant Est. launched it's 2nd edition of HealLand Jordan book.

  On the occasion of The New Year, Johealth seize this......
  Watch Us Today 8th of Sep. On Jordan TV @ 5:40
  HealLand Jordan 2nd Edition
  During menopause, estrogen levels go down. At the same time, bone breakdown (resorption) may increase.
  A Star Sent From Heaven to Dr. Samer Sunna - A Girl

  Dr. Sana Hammouri the First and Only Jordanian Female General Surgeon in the private sector

  Dr. Disi, One of the pioneer Orthopeadics doctors in Jordan

  Sabarini Consultation & Training Est. Offers a lot of services

  For Sale.... Siemens Sonoline SX Sector Ultrasound Scanning Machine

  NEW YORK (Reuters Health) - Older people who exercise are less likely to be depressed,
  LabTechONE is now a client of mayo Medical Laboratories and will provide comprehensive laboratory services
  Chicco, the Italian firm as we all know, is one of the most famous brands world wide....
  JOHEALTH has moved !

  Rheumatoid Arthritis Treatment: The FDA has approved anakinra as adjunctive therapy for..
  FDA APPROVES NEW WEARABLE DEFIBRILLATOR
FOR SERIOUSLY ILL HEART PATIENTS.....
  Breast Tissue Ablation Device: The FDA has approved Cryocare Surgical System....
  Drug for Severe Adult Sepsis: The FDA has approved drotrecogin alfa (activated)...
  On the occasion of Ramadan, Johealth seize this......

  Dr. Najib Layyous, One of the most pioner doctors in Jordan specialized in Infertility...
  Under the unprecedented support of his Royal Majesty King Abdullah II, to further promote the use of internet services for the benefit of the Jordanian people
  A Jordanian Pediatrician invents the first Natural Anti Diarrhea Medication for babies, children and adults.
  FDA issues nationwide alert on the recall of "PIERRE FABRE physicians formula eye makeup remover lotion" because of health risk.
  FDA Approves First Pacemaker For Congestive Heart Failure
  FDA updates safety information for MICONAZOLE VAGINAL cream and suppositories
Copyright © 2000-2026 JoHealth. All rights reserved
info@johealth.com

Powered by Softimpact